Autoimmune hypophysitis: a study of natural course

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Autoimmune hypophysitis: a study of natural course

Autoimmune hypophysitis is a rare autoimmune endocrinopathy. It is possible that the prevalence of autoimmune hypophysitis is underestimated. 1,2 The reported incidence of autoimmune hypophysitis is one in nine million. 3 A recent study reported an estimated incidence of autoimmune hypophysitis in India as 2.4 per ten million population. 4 Increasing recognition of the disease is contributing f...

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Autoimmune hypophysitis.

Autoimmune (lymphocytic) hypophysitis is a rare disease that should be considered in the differential diagnosis of any nonsecreting pituitary mass, especially when occurring during pregnancy or postpartum. We have analyzed 370 articles published from January 1962 to October 2004 and identified a total of 379 patients with primary lymphocytic hypophysitis. The present review synthesizes the clin...

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[Ipilimumab, a cause of autoimmune hypophysitis].

Hypophysitis represents a heterogeneous group of inflammatory lesions affecting the pituitary gland with a complex pathogenesis and is insufficiently characterized. The different types belong to the group of non-hormone secreting sellar masses, with which they share clinical, and sometimes also radiographic, presentation. These similarities make differential diagnosis difficult in the absence o...

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Novel autoantigens in autoimmune hypophysitis.

BACKGROUND Pituitary autoantibodies are found in autoimmune hypophysitis and other conditions. They are a marker of pituitary autoimmunity but currently have limited clinical value. The methods used for their detection lack adequate sensitivity and specificity, mainly because the pathogenic pituitary autoantigen(s) are not known and therefore antigen-based immunoassays have not been developed. ...

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Autoimmune hypophysitis: a single centre experience.

INTRODUCTION Autoimmune hypophysitis (AH) is a rare primary autoimmune inflammatory disorder involving the pituitary gland. METHODS A retrospective analysis of the clinical features and outcome of patients diagnosed with AH between 1988 and 2006, was carried out. RESULTS 15 patients (14 females and one male) with AH were identified. Three patients presented in the peripartum period. Headach...

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ژورنال

عنوان ژورنال: International Journal of Research in Medical Sciences

سال: 2016

ISSN: 2320-6071

DOI: 10.18203/2320-6012.ijrms20161461